Platelet-Rich Plasma or Hyaluronate in the Management of Osteochondral Lesions of the Talus

Osteochondral lesions of the ankle treated with intra-articular injections of PRP and HA resulted in a decrease in pain scores and an increase in function for at least 6 months, with minimal adverse events. Platelet-rich plasma treatment led to a significantly better outcome than HA. Omer Mei-Dan, Michael R. Carmont, Lior Laver, Gideon Mann, Nicola Maffulli, Meir Nyska. AJSM: Published online before print January 17, 2012. PDF