Prolonged Versus Standard Duration Venous Thromboprophylaxis in Major Orthopedic Surgery: A Systematic Review.

Conclusion: Prolonged prophylaxis decreases the risk for venous thromboembolism, PE, and DVT while increasing the risk for minor bleeding in patients undergoing total hip replacement. Sobieraj DM, Lee S, Coleman CI, Tongbram V, Chen W, Colby J, Kluger J, Makanji S, Ashaye AO, White CM. Ann Intern Med. 2012 Mar 12. [Epub ahead of print] PMID: 22412039 Free Full Text