Open PubMed with NMCP LinkOut Before Accessing Articles

Open PubMed LinkOut Prior to Accessing Articles

Tuesday, January 31, 2012

Trying to keep current with clinical guidelines, Review of Journal Watch Hospital Medicine Blackberry app

The use of the SkyScape platform has been previously reviewed by iMedicalApps for the bolt-on app of Outlines in Clinical Medicine: SkyScape review – Outlines in Clinical Medicine.

The breathtaking speed of modern day research results in physicians being besieged with hundreds of new clinical pearls  in their own field alone. iMedicalApps

An en bloc approach to CT perfusion for the evaluation of limb ischemia

We examine volumetric CT perfusion in soft tissues of the entire foot with an en bloc technique to provide a meaningful measure of differentiation between mild and major vascular impairment. With Institutional Review Board approval, 22 healthy male subjects between the ages of 21 and 50 (mean 37) were enrolled. Volumetric computed tomography using an en bloc technique was conducted on 14 subjects for validation while unilateral vascular obstruction was simulated in the calves of the remaining 8 subjects. Perfusion estimates were made using in-house software and differences in perfusion estimates between feet were evaluated with Student's t-test at 95% confidence. Subjects with simulated major vascular obstruction (calf blood pressure cuff inflated to 200 mmHg) showed significantly higher ratios of perfusion estimates between the unobstructed and obstructed foot compared to subjects with simulated mild vascular obstruction (cuff inflated to 120 mmHg), mean 4.6, SD 2.6 vs. mean 1.3, SD 0.2; P = 0.05. CT perfusion using an en bloc technique shows promise for the future evaluation of patients with critical limb ischemia and particularly for re-characterization post medical, surgical or endovascular intervention. Barfett J, Velauthapillai N, Kloeters C, Mikulis DJ, Jaskolka JD. Int J Cardiovasc Imaging. 2012 Jan 28. [Epub ahead of print] PMID: 22286394

New methods enable the early detection of Achilles tendon damage

Two biochemical methods, developed at the Centre of Excellence for High Field Magnetic Resonance at the MedUni Vienna by Vladimir Juras from the University Department of Radiodiagnostics, are enabling Achilles tendon damage to be visualised at an early stage. The processes used are sodium imaging and T2 mapping. MedicalXpress

Emerging MRI Technologies for Imaging Musculoskeletal Disorders Under Loading Stress [Free].

Musculoskeletal conditions are the most common cause of disability in the United States. The differential diagnosis of nonspecific musculoskeletal complaints is challenging and the use of imaging modalities, such as magnetic resonance imaging (MRI), is often required to establish a diagnosis, determine treatment, or monitor disease progression. Although MRI is widely used in medicine today, there remains considerable uncertainty as to the optimal imaging approach for most musculoskeletal conditions. Agency for Healthcare Research and Quality (US); November 2011.

Updates to Surgical Intern Survival Guide improve its utility and functionality

In the initial review of Surgical Intern Survival Guide , we concluded that the app was a simple starting point that could help the fresh surgical interns get their bearings.

In the few months since our review, the authors have given the app a facelift, in both appearance and content. iMedicalApps

Making the most of your CT scan

X-ray photography has been used for decades for medical purposes. Now, scientists have found new ways of obtaining precise and comprehensive data from x-ray computer tomography. In the project BIO-CT-EXPLOIT, an international team of mathematicians, physicists, and engineers figured out new ways to extract valuable information from the data obtained in CT scans. The research project has led to new computer codes for medical applications. In future, they will be used for bone implants, surgery, and tissue engineering. MedicalXpress

Sunday, January 29, 2012

Off Topic but very interesting in the order of "On the Nature of Things (De rerum natura)" by Lucretius

Radical theory explains the origin, evolution, and nature of life. 

The earth is alive, asserts a revolutionary scientific theory of life emerging from Case Western Reserve University School of Medicine. The trans-disciplinary theory demonstrates that purportedly inanimate, non-living objects—for example, planets, water, proteins, and DNA—are animate, that is, alive. With its broad explanatory power, applicable to all areas of science and medicine, this novel paradigm aims to catalyze a veritable renaissance.

Erik Andrulis, PhD, assistant professor of molecular biology and microbiology, advanced his controversial framework in his manuscript "Theory of the Origin, Evolution, and Nature of Life," published in the peer-reviewed journal, Life (free PDF). His theory explains not only the evolutionary emergence of life on earth and in the universe but also the structure and function of existing cells and biospheres.

Journal of Surgical Education - Articles in Press

Union of an intra-articular distal radius fracture after successive failures of three locking plates: a case report

We report a case of a 30-year old male, who presented with a right distal radius intra-articular fracture complicated by compartment syndrome. He was treated with fasciotomies and fracture fixation with a 3.5 mm LCP (Synthes), followed 7 days later by skin graft. Repeat radiographs 8 weeks later showed a break across the plate at the level of an unfilled screw hole over the fracture. He underwent exchange plating with a 2.4 mm LCP Distal Radius Plate (Synthes). This revision was complicated by an infected wound dehiscence 2 weeks later requiring multiple procedures. Radiographs at 20 weeks showed broken distal screws. A second revision was performed. At 12 months, the fracture had healed clinically and radiologically, but the three distal screws had broken. We discuss the multifactorial failures of the these three attempts at osteosynthesis, and which factors helped achieve osseous union. We also discuss the literature on volar locking plate breakage and conclude with the recommendations to avoid this rare complication.
S. K. Khan and C. Gozzard. Strategies in Trauma and Limb Reconstruction; Jan 2012. PDF

Battlefield applications for handheld ultrasound.

Combat medical care provides unique challenges and opportunities for military medical teams. The austerity of the environment severely limits access to many diagnostic and therapeutic tools. Because of their compact size, handheld ultrasound (US) machines are increasingly being used in these constrained environments. A growing body of literature documents the diagnostic utility of handheld US for trauma encountered in the battlefield. Furthermore, US guidance may assist in the performance of some procedures performed in battlefield medical care. This review will provide an overview of the history, current status, limitations and potential future of US utility for the battlefield. Nations JA, Browning RF. Ultrasound Q. 2011 Sep;27(3):171-6. Review. PMID: 21873854

Medtronic’s Aquamantys SBS 5.0 Sheathed Bipolar Sealer Cleared in U.S. for Spinal Surgeries

The SBS 5.0 Sheathed Bipolar Sealer gives spine surgeons the ability to optimize speed and continuity in surgical cases by providing hemostatic sealing capabilities for both incised soft tissue (e.g., cut muscle) and epidural veins with a single device. Like other devices in the Aquamantys line, the SBS 5.0 uses Transcollation® technology, a combination of radiofrequency energy and saline that has been shown to reduce blood loss and improve visualization when used during spine procedures. Reductions in blood loss during surgery have been linked to reduced blood transfusion rates and decreased surgical time. MedGadget

UT Arlington engineer developing 'Biomask' to aid soldiers recovering from facial burns

UT Arlington engineers working with Army surgeons are developing a pliable, polymer mask embedded with electrical, mechanical and biological components that can speed healing from disfiguring facial burns and help rebuild the faces of injured soldiers. MedicalXpress

Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain.

These results highlight the importance of signaling to translation control in peripheral sensitization of nociceptors and provide further evidence for activation of AMPK as a novel treatment avenue for acute and chronic pain states. Tillu DV, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ. Mol Pain. 2012 Jan 23;8(1):5. [Epub ahead of print] PMID: 22269797 Free Article

TED: Brian Goldman: Doctors make mistakes. Can we talk about that? - Brian Goldman (2011)

Every doctor makes mistakes. But, says physician Brian Goldman, medicine's culture of denial (and shame) keeps doctors from ever talking about those mistakes, or using them to learn and improve. Telling stories from his own long practice, he calls on doctors to start talking about being wrong. TED Talks

American Journal of Sports Medicine [Epub ahead of print]