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Saturday, October 15, 2011

Military Orthopedics: historical and overview (PubMed)

A Medical Corps team of the 1st MASH, X Corps, Korea, perform
s a front-line operation on a battle wounded soldier. L-R Cpl. Bob
 Crain of Los Angeles, CA; surgical technician; Lt. (jg) Bruce
 Meiere of Berlinger, CA; Navy Surgeon; Capt. John J. Wilsey
 of Newark, NY, surgeon; and Lt. Marie Smarz of Shelton, Conn., ANC.
14 Feb. 1951. Photo from AMEDD.
Orthopedic surgery. Orthopedic surgery is a specialty of surgery dedicated to the prevention, diagnosis, and treatment of diseases and injuries of the musculoskeletal system in all age groups. Careers in orthopedic surgery span the spectrum from general orthopedics to those of subspecialty expertise in orthopedic trauma, hand, pediatrics, total joint, foot and ankle, sports medicine, and oncology to name a few. Gehrig LM. Am J Surg. 2011 Sep;202(3):364-8. PMID: 21871990

Galileo's contribution to modern orthopaedics. Galileo Galilei (1564-1642), world-renowned Italian mathematician, astronomer, physicist and philosopher, made many contributions to science. The objective of this study is to demonstrate that Galileo's discovery of scaling principles permitted others to define and advance orthopaedic research and clinical sciences. Jastifer JR, Toledo-Pereyra LH, Gustafson PA. J Invest Surg. 2011;24(4):141-4. PMID: 21675848

Search History
SearchMost Recent QueriesTimeResult
Search "Orthopedics/history"[MeSH Major Topic] AND (military OR navy OR naval) Limits: Humans, Historical Article, English10:20:0018

Neuere Med Wiss Quellen Stud. 2011;26:112-38. No abstract available. PMID: 21932478
2. Orthopedic surgery in the United States Army: a historical review. Schoenfeld AJ. Mil Med. 2011 Jun;176(6):689-95. PMID: 21702390
J Bone Joint Surg Am. 2009 Apr;91(4):998-1006. No abstract available. PMID: 19339587 Cited by 6
4. As history repeats itself, unexpected developments move us forward. Gailey R. J Rehabil Res Dev.  2007;44(4):vii-xiv. No abstract available. PMID: 18247244 Free Article
5. Raoul Hoffmann and his external fixator. Schwechter EM, Swan KG. J Bone Joint Surg Am. 2007 Mar;89(3):672-8. No abstract available. PMID: 17332118
6. Louis Stromeyer (1804-76): German orthopaedic and military surgeon and his links with Britain. Smith PF. J Med Biogr. 2006 May;14(2):65-74. PMID: 16607405
Clin Orthop Relat Res. 2004 Dec;(429):306-15. PMID: 15577503
8. Eugen Bircher (1882-1956) the first knee surgeon to use diagnostic arthroscopy. Kieser CW, Jackson RW. Arthroscopy. 2003 Sep;19(7):771-6. PMID: 12966386
10. 1970 report on bone tuberculosis and Dr. Phil Moore's retirement. Poulson S. Alaska Med. 2000 Jul-Sep;42(3):85-8. No abstract available. PMID:1 1042941
Clin Orthop Relat Res. 1996 Apr;(325):4-9. No abstract available. PMID: 8998897
14. Robert Jones: father of modern orthopaedic surgery. Cope R. Bull Hosp Jt Dis. 1995;54(2):115-23. PMID: 8770454
15. H. Winnett Orr and the Nebraska Orthopaedic Hospital. Japp PM, Connolly JF. Nebr Med J. 1985 Nov;70(11):401-8. No abstract available. PMID: 3906413
16. Orthopaedic aspects of mediaeval medicine. Beasley AW. J R Soc Med. 1982 Dec;75(12):970-5. No abstract available. PMID: 6757434 Free PMC Article
17. Orthotics in America: past, present and future. Nickel VL. Clin Orthop Relat Res. 1974 Jul-Aug;(102):10-7. No abstract available. PMID: 4423249
18. Military contributions to the development of orthopaedic surgery by the Armed Forces, U.S.A. Since World War I. Brav EA. Clin Orthop Relat Res. 1966 Jan-Feb;44:115-26. No abstract available. PMID: 5325767 Cited by 5

Naval Medical Center Portsmouth: the serendipitous history of discovery and development surrounding the "Hospital Point" area and its Naval Hospital in Portsmouth. (1558 - 2000) PDF

Friday, October 14, 2011

Rebuilding Soldiers Transformed By War Injuries

Improvements in medical care and equipment mean fewer troops are dying on the battlefield. But more troops are returning home severely wounded, with injuries that require lifelong care and cost millions of dollars in medical bills.

On Thursday's Fresh Air (Transcript), veteran combat reporter David Wood talks about some of the challenges that severely wounded soldiers face when they return from Afghanistan and Iraq. Wood is the author of a new 10-part series for The Huffington Post called "Beyond the Battlefield" that examines some of those challenges and setbacks. Listen to the Story (43 minutes)    NPR

New Ortho Books Soon to be Released

Handbook of Splinting and Casting: Mobile Medicine Series by Stephen R. Thompson MBBS MEd FRCSC and Dan A. Zlotolow MD (Oct 31, 2011)

Master Techniques in Orthopaedic Surgery: Orthopaedic Oncology and Complex Reconstruction by Franklin H. Sim, Peter F.M. Choong and Kristy L. Weber (Nov 2, 2011)

The Diabetic Foot: Medical and Surgical Management by Aristidis Veves, John M. Giurini and Frank W. LoGerfo (Nov 1, 2011)

Perioperative Care of the Orthopedic Patient: The Hospital for Special Surgery Manual by Charles N. Cornell, Ronald MacKenzie and Stavros G. Memtsoudis (Nov 1, 2011)

Manual of INTERNAL FIXATION: Techniques Recommended by the AO-ASIF Group by Maurice E. Müller, Robert Schneider, Hans Willenegger and Martin Allgöwer (Nov 29, 2011)

Penetrating Trauma: A Practical Guide on Operative Technique and Peri-Operative Management by George C. Velmahos, Elias Degiannis and Dietrich Doll (Nov 28, 2011)

Journal of Surgical Education: articles in press

1 Academic Time at a Level 1 Trauma Center: No Resident, No Problem? In Press, Corrected Proof, Available online 6 October 2011; Kazuhide Matsushima, Rebecca M. Dickinson, Eric W. Schaefer, Scott B. Armen, Heidi L. Frankel PDF

2 Learning Surgical Communication, Leadership and Teamwork Through Simulation. In Press, Corrected Proof, Available online 6 October 2011; Margaret Bearman, Robert O'Brien, Adrian Anthony, Ian Civil, Brendan Flanagan, Brian Jolly, David Birks, Mary Langcake, Elizabeth Molloy, Debra Nestel PDF

3 Current Approaches to Journal Club by General Surgery Programs Within the Southwestern Surgical Congress. In Press, Corrected Proof, Available online 6 October 2011; Vanessa Shifflette, Chris Mitchell, Alicia Mangram, Ernest Dunn PDF

See also: Volume 68, Issue 6 pp. e1-e8, 447-568 (November-December 2011)

AAOS Now Top Stories: October 2011 Issue

Board approves VTED prevention guidelines

HHS tightens conflict-of-interest rules for researchers

Looking for an edge: Steroids, supplements, and “vitamins”

Why do disparities in joint care continue?

The effects of tourniquet on intraocular pressure during knee surgery.

Pneumatic tourniquet may cause a significant IOP increase in patients performing knee surgery under general anesthesia. Bulut NG, Karaaslan K, Ozturan KE, Cakici H, Kocoglu H. Middle East J Anesthesiol. 2011 Feb;21(1):93-8. PMID: 21991739

Iatrogenic ulnar nerve injury after pin fixation and after antegrade nailing of supracondylar humeral fractures in children.

Background and purpose Ulnar nerve injury may occur after pinning of supracondylar fractures in children. We describe the outcome and compare the rates of iatrogenic injuries to the ulnar nerve in a consecutive series of displaced supracondylar humeral fractures in children treated with either crossed pinning or antegrade nailing.  Eberl R, Eder C, Smolle E, Weinberg AM, Hoellwarth ME, Singer G. Acta Orthop. 2011 Oct;82(5):606-9. PMID: 21992087 PDF

Operative management of Hoffa fractures-A prospective review of 18 patients.

Hoffa fractures represent coronal fractures of the femoral condyles. Isolated Hoffa fractures are rare and current management of these fractures is based on a few descriptions in literature. The goal of the study was to prospectively analyse the clinico-radiological and functional outcome following open surgical treatment.
 Gavaskar AS, Tummala NC, Krishnamurthy M. Injury. 2011 Oct 10. [Epub ahead of print] PMID: 21993368 PDF

What is the effect of compartment syndrome and fasciotomies on fracture healing in tibial fractures?

Acute compartment syndrome (ACS) in tibial diaphyseal fractures has been associated with such complications as infection, delayed fracture healing or non-union, sensory and motor deficits, deformities, and poor functional outcome. Essential condition of an uncomplicated recovery is early diagnosis with prompt decompression. A comprehensive review of the literature was performed to evaluate the impact of compartment syndrome and leg fasciotomies on the time to fracture union and the incidence of delayed union and non-union in tibial diaphyseal fractures. Reverte MM, Dimitriou R, Kanakaris NK, Giannoudis PV. Injury. 2011 Oct 10. [Epub ahead of print] PMID: 21993369 PDF

Platelet-Rich Plasma for the Replenishment of Bone.

This review examines the use of platelet-rich plasma (PRP) in the treatment of bone injuries and to stimulate bone formation. Studies examining both in vivo bone healing and in vitro actions of PRP on osteoblasts are reviewed.  Iqbal J, Pepkowitz SH, Klapper E. Curr Osteoporos Rep. 2011 Oct 14. [Epub ahead of print] PMID:  21993865

Sports Activity After Short-Stem Hip Arthroplasty.

Patients with a short-stem hip implant can return to a good level of activity postoperatively. Participation in sports almost reached similar levels as preoperatively but with a shift from high- to low-impact activities. This seems desirable from a surgeon's point of view but should also be communicated to the patient before hip replacement. Schmidutz F, Grote S, Pietschmann M, Weber P, Mazoochian F, Fottner A, Jansson V.
Am J Sports Med. 2011 Oct 12. [Epub ahead of print] PMID: 21993977 PDF

Infection mitigation efficacy of photoactive titania on orthopedic implant materials.

In order to impede infection and achieve accelerated wound healing in the postorthopaedic surgery patients, a simple and benign procedure for creating nanotubular or nanofibrillar structure of photoactive TiO(2) on the surface of Ti plates and wires is described. Azad AM, Hershey R, Aboelzahab A, Goel V. Adv Orthop. 2011;2011:571652. Epub 2011 Mar 10. PMID: 21994891

Sclerostin and Its Association with Physical Activity, Age, Gender, Body Composition, and Bone Mineral Content in Healthy Adults.

In healthy adults, sclerostin serum levels correlate positively with age, BMI, and BMC and negatively with osteocalcin and calcium. Further studies in larger populations are needed to confirm our findings and to better understand their clinical implications. Amrein K, Amrein S, Drexler C, Dimai HP, Dobnig H, Pfeifer K, Tomaschitz A, Pieber TR, Fahrleitner-Pammer A. J Clin Endocrinol Metab. 2011 Oct 12. [Epub ahead of print] PMID: 21994959

Doctor discovers ultrasound treatment speeds up healing time of broken bones

SCOTS doctors have found that ultrasound treatment can reduce the healing time for broken bones by up to a third.

Orthopaedic surgeon Angus MacLean has been using the technology at Glasgow's Royal Infirmary's fracture clinic. And the results of his trials have astonished medics.

He said: "Before we used ultrasound, many injuries would heal with some difficulty - and some would not heal at all. Evidence suggests ultrasound speeds things up by about 40 per cent. It vibrates the cells, which stimulates healing and regeneration in the bone. Daily Record

Headache are among the top reasons for medical evacuation of soldiers

Headaches, a virtually universal human complaint at one time or another, are among the top reasons for medical evacuation of military personnel from Iraq and Afghanistan, and for ongoing depletion of active-duty ranks in those countries, according to research led by Johns Hopkins specialists. Just one-third of soldiers sent home because of headaches return to duty in either place, the research shows.

The findings, published online in Cephalalgia, the journal of the International Headache Society, highlight one of the fastest-growing causes of medical evacuations from the two prolonged military conflicts. They are a significant and worrisome contributor to the depletion of military units overseas, Cohen says.

Cohen says a significant number of headaches were the result of damage to or pressure on the occipital nerve, located in the back of the head. This is often caused by the heavy Kevlar helmets soldiers are required to wear on patrol and for long periods.

Thursday, October 13, 2011

Orthopedic injuries before combat deployment--will the soldiers be ready for combat when their unit is called upon?

Orthopedic injuries can occur anytime; but, before a known deployment, they can affect mission planning for commanders. A longitudinal cohort study of 158 soldiers with an orthopedic injury approximately 3 months before, and after, initial deployment in support of Operation Iraqi Freedom from a U.S. Army Brigade Combat Team was performed.  Frank AJ. Mil Med. 2011 Sep;176(9):1015-8. PMID: 21987959 PDF

Subscapularis tears.

From WikiMedia Commons
The subscapularis muscle is the largest and strongest muscle of the rotator cuff. It plays an essential role in the stability and function of the shoulder. Tears of the subscapularis tendon are more frequent than previously estimated. The worldwide use of arthroscopy in rotator cuff surgery has allowed to recognize the true prevalence of subscapularis lesions, as it permits to visualize the articular side where partial tears are usually localized. Subscapularis tears are generally non-traumatic, arising from intrinsic degeneration, subcoracoid and/or anterosuperior impingement. Longo UG, Berton A, Marinozzi A, Maffulli N, Denaro V. Med Sport Sci. 2012;57:114-21. Epub 2011 Oct 4. PMID: 21986050

See also:
Subscapularis tendon tears.  Lyons RP, Green A. J Am Acad Orthop Surg. 2005 Sep;13(5):353-63. Review. PMID: 1614836 PDF  Cited by 26

Forget about peripheral mhealth devices, researchers use smartphone video camera to monitor useful vital signs

Researchers at Worcester Polytechnic Institute have developed a smartphone app that uses a camera to measure key vital signs. The type of technology used by the Worcester researchers is far and above more useful than a simple heart rate monitor, such as the Instant Heart Rate app.

Recently, the Instant Heart app makers received millions in funding – I hope it wasn’t based solely on the heart rate monitor app they have developed. Having a a patient’s heart rate alone isn’t that useful for a clinician, and it’s extremely easy to measure your heart rate on your own, just put your fingers to your wrist or neck.

But the work by Worcester researchers is completely different, exciting, and unlike the Instant Heart Rate app, could have real impact.  The researchers have developed an application that uses the smart phone’s built in video camera to now only measure heart rate, but heart rhythm, respiratory rate, and blood oxygen level (pulse ox) – all without needing a peripheral device – amazing.  iMedicalApps

Wednesday, October 12, 2011

Afghanistan Theater Receives State-of-the-Art MRI Systems

111006-O-KK908-026 CAMP BASTION, Afghanistan (Oct. 5, 2011) An MRI machine is set up at the Role 3 Medical Facility at Joint Operating Base, Bastion, Afghanistan. (Royal Air Force photo by Sgt. Mitch Moore/Released)
The top doctor for the U.S. Navy and Marine Corps announced the delivery of two mobile Magnetic Resonance Imaging (MRI) systems to Afghanistan Oct. 4-7.

Navy Surgeon General Vice Adm. Adam M. Robinson Jr. said that the delivery marked the end of an unprecedented medical equipment procurement initiative to deliver a first-ever MRI capability to a combat theater.

The first mobile MRI system arrived on a mega-cargo Antonov AN 124 Russian aircraft Oct 4. Weighing more than 70,000 pounds, the MRI and its accompanying supplies were unloaded using a prime mover, two flatbeds, and a forklift to travel to its final destination at the Role 3 hospital at Camp Bastion. A second MRI was delivered to the Role 3 hospital in Kandahar Oct 7, and progress continues on both systems for final installation, prepping and testing.

Orthopedic Clinics of North America. October, 2011; 42(4)

Lumbar Intervertebral Disk Degeneration Samartzis D PDF

Structure and Biology of the Intervertebral Disk in Health and Disease Chan WC PDF

Intervertebral Disk Nutrition: A Review of Factors Influencing Concentrations of Nutrients and Metabolites Grunhagen T PDF

Genetics of Lumbar Disk Degeneration: Technology, Study Designs, and Risk Factors Yu-Ping KP PDF

Biomechanics of Intervertebral Disk Degeneration Inoue N PDF

Diagnostic Tools and Imaging Methods in Intervertebral Disk Degeneration Majumdar S PDF

Management of Degenerative Disk Disease and Chronic Low Back Pain Karppinen J PDF

Adjacent Level Disk Disease--Is it Really a Fusion Disease? Lund T PDF

Prosthetic Total Disk Replacement--Can We Learn from Total Hip Replacement? Mayer HM PDF

Stem Cell Regeneration of the Intervertebral Disk Sakai D PDF

Gene Therapy for Intervertebral Disk Degeneration Woods BI PDF

Tissue Engineering for Intervertebral Disk Degeneration Leung VY PDF

Emerging Technologies for Molecular Therapy for Intervertebral Disk Degeneration Bae WC PDF

Recent High Energy Trauma Articles from PubMed

1. Primary and Secondary Skeletal Blast Trauma*(,†). Christensen AM, Smith VA, Ramos V, Shegogue C, Whitworth M. J Forensic Sci. 2011 Oct 7. doi: 10.1111/j.1556-4029.2011.01938.x. [Epub ahead of print] PMID: 21981586
2. Surgical treatment of displaced acetabular fractures. Milenković S, Saveski J, Radenković M, Vidić G, Trajkovska N. Srp Arh Celok Lek. 2011 Jul-Aug;139(7-8):496-500. PMID: 21980661
3. [Calcaneus fractures]. Clare MP, Sanders RW. Unfallchirurg. 2011 Oct;114(10):869-76. German (An English full text version of this article is available at SpringerLink as supplemental.). PMID: 21979889

Tuesday, October 11, 2011

Bilateral Simultaneous Traumatic Upper Arm Compartment Syndromes Associated with Anabolic Steroids.

Acute compartment syndrome, a surgical emergency, is defined as increased pressure in an osseofascial space. The resulting reduction of capillary perfusion to that compartment requires prompt fasciotomy. Treatment delay has a poor prognosis, and is associated with muscle and nerve ischemia, resultant infarction, and late-onset contractures. Erturan G, Davies N, Williams H, Deo S. J Emerg Med. 2011 Oct 7. [Epub ahead of print] PMID: 21982985 PDF

Remission after treatment of osteoarticular infections due to Pseudomonas aeruginosa versus Staphylococcus aureus: a case-controlled study.

Despite a similar number of surgical interventions and longer antibiotic treatment, osteoarticular infections due to P. aeruginosa tended towards a lower remission rate than infections due to S. aureus in general or MRSA in particular. Seghrouchni K, van Delden C, Dominguez D, Benkabouche M, Bernard L, Assal M, Hoffmeyer P, Uçkay I. Int Orthop. 2011 Oct 5. [Epub ahead of print] PMID: 21983903

A Prospective Multicenter Study on the Outcome of Type I Collagen Hydrogel-Based Autologous Chondrocyte Implantation (CaReS) for the Repair of Articular Cartilage Defects in the Knee.

The Cartilage Regeneration System (CaReS) is a novel matrix-associated autologous chondrocyte implantation (ACI) technique for the treatment of chondral and osteochondral lesions (Outerbridge grades III and IV). For this technology, no expansion of the chondrocytes in a monolayer culture is needed, and a homogeneous cell distribution within the gel is guaranteed. Schneider U, Rackwitz L, Andereya S, Siebenlist S, Fensky F, Reichert J, Löer I, Barthel T, Rudert M, Nöth U. Am J Sports Med. 2011 Oct 7. [Epub ahead of print] PMID: 21984690 PDF

Monday, October 10, 2011

Smartphone ultrasound device launches commercially

In February Mobisante announced that the FDA had cleared its handheld, smartphone-enabled ultrasound offering, and while the company hoped to launch “a long time ago,” MobiUS only just became commercially available in recent days, Mobisante co-founder and CTO David Zar told MobiHealthNews. The mobile ultrasound imaging system includes a Toshiba Windows Mobile-powered smartphone, an ultrasound probe and the company’s software. Mobisante’s device is intended for ultrasound imaging, analysis and measurement in fetal/OB, abdominal, cardiac, pelvic, pediatric, mucoskeletal, and peripheral vessel imaging. The smartphone-based ultrasound system can leverage both cellular and WiFi to send images for diagnosis, second opinion, or to a Picture Archiving and Communication System (PACS) for storage.  MobiHealthNews

Computer-assisted navigation and musculoskeletal sarcoma surgery.

Despite advances in medical, surgical, and radiation oncology, deep-seated bone sarcomas that require large osseous resections continue to present resection and reconstructive challenges to musculoskeletal surgeons. Cheong D, Letson GD. Cancer Control. 2011 Jul;18(3):171-6. Review. PMID: 21666579 PDF

The American Journal of Sports Medicine: PreView articles

1. Osteochondral Lesion of the Talus: Could Age Be an Indication for Arthroscopic Treatment? PDF

2. A Prospective Multicenter Study on the Outcome of Type I Collagen Hydrogel-Based Autologous Chondrocyte Implantation (CaReS) for the Repair of Articular Cartilage Defects in the Knee

A retrospective study into the levels of evidence presented at the Combined Services Orthopaedic Society annual meeting.

The role of Evidence Based Medicine in clinical care is to provide a framework for the integration of expertise, current evidence and the needs of the individual patient. Research presented at scientific meetings is an important source of such evidence, informing clinical decision making both on military operations and in home nation health care systems. The aim of this study is to review the levels of evidence presented at the Combined Services Orthopaedic Society (CSOS) and two other related scientific meetings. Bonner TJ, Mountain A, Eardley WG, Clasper JC. J R Army Med Corps. 2011 Sep;157(3):233-6. PMID: 21977713

European Journal of Orthopaedic Surgery & Traumatology: recent articles

Delayed surgical treatment of displaced midshaft clavicle fracture using Herbert cannulated screw with intramedullary bone graft

Posterior bilaterotricipital approach for surgical treatment of children’s Gartland Type III supracondylar humeral fractures

Section of the sciatic nerve by a metal acetabulum reinforcement ring: a literature review through one case

Total dislocation of the talus

Surgical reconstruction of comminuted coronoid fracture in terrible triad injury of the elbow

Vascular complications following total hip arthroplasty: a case study and a review of the literature

Antegrade locked intramedullary nailing versus dynamic compression plating for humeral shaft fractures in adults: a meta-analysis of randomized controlled trials

Apple tries to help doctors categorize medical apps, but falls short

A few months ago we started receiving e-mails from developers stating Apple was reaching out to them and was going to put certain medical apps from the main iOS store into specific categories in iTunes.

Obviously, we were excited to hear this, as we’ve written before how the Medical Category in the iOS store is cluttered with apps that health care professionals don’t need.

Unfortunately, with the rollout of the “Apps for Healthcare Professionals” category in iTunes, we’ve been more disappointed than excited. The imedicalapps team was expecting apps to be separated by specialities — or at least by broad medical professionals, such as “nursing”, “EMS”, and “physician centered” — but this was not the case. Apart from the issue with sub-categories, Apple missed the mark with not only the apps that were included, but also the extremely useful apps they excluded. iMedicalApps

Springer "Online First" Ortho Related Articles

1. Navigation in minimally invasive unicompartmental knee arthroplasty has no advantage in comparison to a conventional minimally invasive implantation

2. Surgical treatment of acute fingernail injuries PDF

3. Pediatric scoliosis

4. Articular cartilage of the posterior condyle can affect rotational alignment in total knee arthroplasty

Comparison of 2- and 3-Dimensional Shoulder Ultrasound to Magnetic Resonance Imaging in a Community Hospital for the Detection of Supraspinatus Rotator Cuff Tears with Improved Worktime Room Efficiency.

3D US of the shoulder is as accurate as 2D US when compared with MRI for the diagnosis of full- and partial-thickness supraspinatus rotator cuff tears, and 3D US examination significantly reduced the time between the initial scan and the radiologist interpretation, ultimately improving workplace efficiency. Co S, Bhalla S, Rowan K, Aippersbach S, Bicknell S. Can Assoc Radiol J. 2011 Oct 4. [Epub ahead of print] PMID: 21975160

Anthony Atala on growing new organs (Video - watch at home. Blocked by DoD)

Anthony Atala's state-of-the-art lab grows human organs -- from muscles to blood vessels to bladders, and more. At TEDMED, he shows footage of his bio-engineers working with some of its sci-fi gizmos, including an oven-like bioreactor (preheat to 98.6 F) and a machine that "prints" human tissue. TED Talks

Ampio Announces the Presentation of a Publication on Ampion(TM), its Drug Candidate to Address Human Inflammation, at the American Association of Orthopedic Surgery

About the Ampion(TM) in Knee (AIK) Trial
In this study, Ampion(TM) is injected into the knees of patients with osteoarthritis of the knee in conjunction with standard therapy, including steroids, aiming to demonstrate a reduction in pain and improved range of motion compared to placebo. The observation period in this study is only 72 hours, thus results of this trial are anticipated to be available in the short term.

About Ampion(TM)
Ampion(TM) is a patented small molecule with non- steroidal anti-inflammatory and analgesic properties that is naturally produced by humans in response to injury. Because it is present in commercially available human serum albumin which has been given to millions of people over several decades, it can be considered to be a biological. MarketWatch 

Beyond The Battlefield: From A Decade Of War, An Endless Struggle For The Severely Wounded

The Defense Department uses a measure called the Military Injury Severity Score to categorize wounds. In Afghanistan, the severity scores have increased steadily since 2006, the Army reported in June.

The number of American soldiers who lost at least one limb in combat doubled from 86 in 2009 to 187 last year, while the number with multiple limb loss tripled, from 23 in 2009 to 72 last year. Those in need of blood transfusions of 10 units of blood or more (the human body holds a total of 10 units of blood) rose during that 12-month period from 91 to 165.

And triple amputees like Tyler Southern are becoming more common. Their ranks have nearly doubled this year from the total of all triple amputees seen over the past eight years of war, the Army said in its report, "Dismounted Complex Blast Injury." Huffington Post

A Prospective, Randomized Evaluation of Acellular Human Dermal Matrix Augmentation for Arthroscopic Rotator Cuff Repair.

Acellular human dermal matrix augmentation of large (>3 cm) cuff tears involving 2 tendons showed better ASES and Constant scores and more frequent intact cuffs as determined by gadolinium-enhanced MRI. Intact repairs were found in 85% of the augmented group and 40% of the nonaugmented group (P < .01). No adverse events related to the acellular human dermal matrix were observed.Barber FA, Burns JP, Deutsch A, Labbé MR, Litchfield RB. Arthroscopy. 2011 Oct 5. [Epub ahead of print] PMID: 2197843

Sunday, October 9, 2011

A kinematic and kinetic analysis of drop landings in military boots.

The purpose of this study was to examine knee valgus in drop landings during three different footwear conditions and to examine the ground reaction forces exhibited during the drop landing in the three different footwear conditions. Oliver GD, Stone AJ, Booker JM, Plummer HA. J R Army Med Corps. 2011 Sep;157(3):218-21. PMID: 21977709

Bone Marrow-Derived Mesenchymal Stem Cells Obtained During Arthroscopic Rotator Cuff Repair Surgery Show Potential for Tendon Cell Differentiation After Treatment With Insulin.

The purpose of this study was to determine whether a one-time physiologic dose of insulin when compared with the growth factors insulin-like growth factor 1, β-fibroblastic growth factor, and growth differentiation factor 5 is capable of differentiating bone marrow-derived mesenchymal stem cells (MSCs) into tendon. Mazzocca AD, McCarthy MB, Chowaniec D, Cote MP, Judson CH, Apostolakos J, Solovyova O, Beitzel K, Arciero RA.
Arthroscopy. 2011 Oct 4. [Epub ahead of print] PMID: 21978434

Intraoperative Cooling of Iliac Bone Graft: An Experimental Evaluation of Cell Viability.

Storing iliac bone graft on ice rather than at room temperature optimizes cellular viability, with cooled bone demonstrating 22.0% more active cells after 2 hours. Cellular loss of cooled graft plateaued after 4 hours. Clinically, the iliac graft should be maintained on ice until placed into the alveolar cleft. Hassanein AH, Greene AK, Arany PR, Padwa BL. J Oral Maxillofac Surg. 2011 Oct 4. [Epub ahead of print] PMID: 21978716

The Journal of the American Academy of Orthopaedic Surgeons. 2011 Oct;19(10) via PubMed

 1. Galeazzi fracture. Atesok KI, Jupiter JB, Weiss AP. J Am Acad Orthop Surg. 2011 Oct;19(10):623-33. PMID: 21980027 
2. The role of high tibial osteotomy in the varus knee. Rossi R, Bonasia DE, Amendola A. J Am Acad Orthop Surg. 2011 Oct;19(10):590-9. PMID: 21980024
3. Pediatric cervical spine trauma. Jones TM, Anderson PA, Noonan KJ. J Am Acad Orthop Surg. 2011 Oct;19(10):600-11. PMID: 21980025

Intramedullary Nailing of Proximal Third Tibial Fractures: Techniques to Improve Reduction

Obtaining and maintaining an acceptable reduction of proximal third tibial fractures can be problematic. Deforming forces acting on the proximal fragment and the spaciousness of the intramedullary canal at this level contribute to this challenge during intramedullary nailing. Several surgical techniques have been developed to address this problem, including the use of a more lateral and proximal starting point, adjunctive plate fixation, blocking screws, semiextended nailing, and most recently the use of a retropatellar portal approach. Familiarity with these techniques is critical to achieving satisfactory results when nailing proximal third tibial fractures. David J. Hak, MD, MBA Orthopedics July 2011;34(7):532. (Full-text HTML)

Allograft Osteochondral Transplantation in the Knee in the Active Duty Population

The purpose of this study is to analyze the role of allograft osteochondral transplantation in the knee in the active duty population, focusing on the patient's ability to remain on active duty following the procedure. A retrospective review was performed on all active duty patients undergoing allograft osteochondral transplantation surgery of the knee at our institution from 2003 to 2011. Medical records were reviewed for patient characteristics and treatment details. Eighteen patients underwent osteochondral transplantation surgery from 2003 to 2011. One of the patients is still in the acute recovery phase of their procedure (<1 year since surgery), and one patient was already in the medical evaluation board (MEB) process at the time of surgery. Of the remaining sixteen patients, nine have either entered or completed the MEB since surgery. Six of the seven patients who have stayed on active duty remain on activity-restricting profiles. The average time from surgery to MEB for these patients was 23.2 months. In the setting of the unique demands of active duty soldiers, osteochondral allograft transplantation does not appear to be conducive to retention on active duty. Scully, William F.; Parada, Stephen A.; Arrington, Edward D. Military Medicine, Volume 176, Number 10, October 2011 , pp. 1196-1201(6)

AMP’D Gear’s Custom Sports Prosthetics

Here’s a three minute HP ad that promotes computer workstations, but gives a look into the operations of AMP’D Gear, a small company that designs prostheses for unusual activities for amputees to be partaking in, like rock climbing and swimming. MedGadget