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Wednesday, January 25, 2012

Research project for peripheral nerve injuries? Imaging live mouse spinal cord will aid trauma therapy

The new spinal cord procedure, described in the Jan. 22 online issue of the journal , involves surgically implanting a window, or chamber with a transparent panel over a live mouse's exposed cord. Fluorescently labeled objects, such as neural cells or blood vessels, are then visualized in 3-D using multiphoton microscopy (invented by Cornell biophysicist Watt W. Webb). MedicalXpress

Comparison of Three-dimensional Isotropic T1-weighted Fast Spin-Echo MR Arthrography with Two-dimensional MR Arthrography of the Shoulder

The accuracy of 3D isotropic FSE MR arthrography may be comparable with that of conventional 2D MR arthrography in the diagnosis of rotator cuff tears and labral lesions with a shorter imaging time. Choo HJ, Lee SJ, Kim OH, Seo SS, Kim JH. Radiology. 2012 Jan 20. [Epub ahead of print] PMID: 22267587

Foot and ankle structure differs between sprinters and non-sprinters

The skeletal structure of the foot and ankle differs significantly between human sprinters and non-sprinters, according to Penn State researchers. Their findings not only help explain why some people are faster runners than others, but also may be useful in helping people who have difficulty walking, such as older adults and children with cerebral palsy.

According to Stephen Piazza, associate professor of kinesiology, the research is the first to use magnetic resonance imaging to demonstrate that sprinters have significantly longer bones in their forefeet than non-sprinters and reduced leverage in their Achilles tendons than non-sprinters.

The researchers took MRI images of the right foot and ankle of each of the subjects. They then used specialized software to analyze the images. The scientists found that the Achilles tendon lever arms of sprinters were 12 percent shorter than those of non-sprinters. They also found that the combined length of the bones in the big toes of sprinters was on average 6.2 percent longer than that of non-sprinters, while the length of another foot bone, the first metatarsal, was 4.3 percent longer for sprinters than for non-sprinters. Their results are reported in the current issue of the Proceedings of the Royal Society B. Eurekalert!

Scientific plagiarism: A growing problem in an era of shrinking research funding

As scientific researchers become evermore competitive for scarce funding, scientific journals are increasing efforts to identify submissions that plagiarize the work of others. Still, it may take years to identify and retract the plagiarized papers and give credit to the actual researchers.

"We need a better system," said Harold Garner, executive director of the Virginia Bioinformatics Institute at Virginia Tech. Garner discussed the problem and solution in a Comment in the January 4, 2012 issue of Nature and in a January 19, 2012 radio interview with NPR's Leonard Lopate. Eurekalert!

Tuesday, January 24, 2012

Recent Military or High-Energy Trauma Related Ortho Articles from PubMed

1. Infection after spanning external fixation for high-energy tibial plateau fractures: is pin site-plate overlap a problem? Laible C, Earl-Royal E, Davidovitch R, Walsh M, Egol KA. J Orthop Trauma. 2012 Feb;26(2):92-7. PMID: 22011631
2. Proximal sural traction neurectomy during transtibial amputations. Tintle SM, Donohue MA, Shawen S, Forsberg JA, Potter BK. J Orthop Trauma. 2012 Feb;26(2):123-6. PMID: 21804416
3. Epidemiology, imaging, and treatment of Lisfranc fracture-dislocations revisited. Kalia V, Fishman EK, Carrino JA, Fayad LM. Skeletal Radiol. 2012 Feb;41(2):129-36. Epub 2011 Mar 23. PMID: 21431438 4. Staged Posterior Tibial Plating for the Treatment of Orthopaedic Trauma Association 43C2 and 43C3 Tibial Pilon Fractures. Ketz J, Sanders R. J Orthop Trauma. 2012 Jan 20. [Epub ahead of print] PMID: 22207206
5. Bone transport techniques in posttraumatic bone defects. Rigal S, Merloz P, Le Nen D, Mathevon H, Masquelet AC; the French Society of Orthopaedic Surgery and Traumatology (SoFCOT). Orthop Traumatol Surg Res. 2012 Jan 17. [Epub ahead of print] PMID: 22257763
6. Femoral neck fracture following hardware removal. Shaer JA, Hileman BM, Newcomer JE, Hanes MC. Orthopedics. 2012 Jan 16;35(1):e83-7. doi: 10.3928/01477447-20111122-34. PMID: 22229620

New tool enhances view of muscles

Simon Fraser University associate professor James Wakeling is adding to the arsenal of increasingly sophisticated medical imaging tools with a new signal-processing method for viewing muscle activation details that have never been seen before.

Fascinated with the mechanics of muscle movement in people and animals, Wakeling has developed a novel method using ultrasound imaging, 3D motion-capture technology and proprietary data-processing software to scan and capture 3D maps of the muscle structure — in just 90 seconds.

Wakeling hopes his research will ultimately lead to new software programs for predicting the outcome of orthopaedic surgeries such as tendon-transfers for treating conditions like cerebral palsy in children. Eurekalert!

New From iMedicalApps

Recent Ultrasound Related Ortho Articles via PubMed

1. Imaging the injured shoulder. Reynolds A. Radiol Technol. 2012 Jan;83(3):261-82. PMID: 22267694
2. CT in children's bones and joints: When, how and common findings. Balassy C, Miller SF. Eur J Radiol. 2012 Jan 18. [Epub ahead of print] PMID: 22264694
3. Procedure-Oriented Sectional Anatomy of the Elbow. Sanchez O, Harrell JS, Chiou-Tan FY, Zhang H, Taber KH. J Comput Assist Tomogr. 2012 Jan;36(1):157-160. PMID: 22261788
4. Biomechanical comparison of different acetabular plate systems and constructs - The role of an infra-acetabular screw placement and use of locking plates. Marintschev I, Gras F, Schwarz CE, Pohlemann T, Hofmann GO, Culemann U. Injury. 2012 Jan 17. [Epub ahead of print] PMID: 22261082
5. Dynamic ultrasound assessment of the effects of knee and ankle position on achilles tendon apposition following acute rupture. Qureshi AA, Ibrahim T, Rennie WJ, Furlong A. J Bone Joint Surg Am. 2011 Dec 21;93(24):2265-70. PMID: 22258772

Monday, January 23, 2012

Textbook Out Soon: Evidence-based Orthopedics: Mohit Bhandari (Editor)

Surgical orthopedic procedures such as hip replacements, arthroscopy or knee replacements are surrounded by pre- and post-operative complications, and there are varying different methods for the procedures themselves. This book, for the first time, brings together the best evidence for treatments as well as any complications. Not only does it cover the evidence base for orthopedic surgery, but also orthopedic conditions requiring medical treatment, and pediatric orthopedics. Using the approved EBM methodology, and edited by teachers of evidence-based medicine, this is a genuine EBM textbook for all orthopedic specialists and trainees.

Mohit Bhandari MD, MSc (McMaster), FRCSC is Associate Professor of Surgery and Associate Member of the Department of Clinical Epidemiology and Biostatistics at McMaster University, Hamilton, Ontario. He also holds a Canada Research Chair. He is Section Editor of Evidence-Based Orthopaedic Surgery, Journal of Orthopaedic Trauma and a co-chair of the McMaster University Evidence-based Medicine course.

Surgeons Having More Success Reattaching Fingers and Thumbs

On average, Bindra (Loyola University Medical Center hand surgeon Dr. Randy Bindra) sees three or four cases per month in which one or more digits have been completely cut off or almost completely severed. The typical patient is a do-it-yourselfer, rather than a professional carpenter who has undergone safety training, Bindra said.

Bindra reattaches bones with tiny plates, screws and pins. He sews nerves and blood vessels together with sutures that are finer than a human hair. In Thompson's case, Bindra also took a vein from a forearm to reconnect blood supply to the thumb. Newswise

“Would you like some Indian food with that operation”? Curcumin Protects Against Ischemia/Reperfusion Injury in Rat Skeletal Muscle.

Administration of curcumin significantly decreased tissue protein carbonyl levels as a marker of protein oxidation activities (PO) in skeletal muscle compared with the injured-untreated group. Curcumin reversed the increase of MDA levels to a considerable extent, thereby confirming its antioxidant role in IRI. Decreased SOD, CAT, and GSH activities by IRI are reversed by the administration of curcumin. Levels of circulating inflammatory cytokines TNF-a and IL-1b were reduced in curcumin-treated group in comparison to the IRI non-treated group. Bank J, Song DH. J Surg Res. 2011 Nov 19. [Epub ahead of print] No abstract available. PMID: 22261585 PDF

Sunday, January 22, 2012

The Foot and Ankle Clinics: Online First

Varus Hindfoot Deformity After Talar Fracture
James A. Sproule, Mark A. Glazebrook, Alastair S. Younger. 26 December 2011   PDF (1057 KB)
The unique anatomy of the talus contributing to three important joints makes its integrity and joint congruency crucial for normal foot function. Consequently, posttraumatic malalignment of the talus ...

Total Ankle Replacement in Ankle Arthritis with Varus Talar Deformity: Pathophysiology, Evaluation, and Management Principles
D. Josh Mayich, Timothy R. Daniels. 14 December 2011 PDF (2076 KB)
VMAA is common in end-stage ankle arthritis with varying and poorly described etiologies. With a greater understanding of VMAA, it is becoming apparent that its pathology has both hereditary and envir...

Distal Tibial Varus
Douglas Beaman, Richard Gellman.  14 December 2011 PDF (241 KB)
The focus of this article is the correction of distal tibial varus deformities utilizing gradual techniques and distraction osteogenesis. Distraction osteogenesis is the formation of new bone after an...

The Varus Ankle and Instability
Georg Klammer, Emanuel Benninger, Norman Espinosa.  14 December 2011 PDF (2967 KB)
Hindfoot varus has been recognized as an anatomic risk factor that promotes chronic lateral ankle instability. Hindfoot varus is present in 8% of patients with ankle instability, and with 28% it is th...

Cavus Foot
Alastair S. Younger. 12 December 2011 PDF (92 KB)

Smartphone aided measurement of spinal deformity proves superior to manual methods

Certain smartphone applications can provide quick assistance in the diagnosis  of disease.  One such example is Cobbmeter, a smartphone application designed for the measurement of Cobb angle on Apple’s iPhone. The Cobb angle measures the degree of spinal deformity which exists in a person with scoliosis. iMedicalApps

New Ortho Issues from Audio-Digest

Volume 35, Issue 03
February 7, 2012
Sports injuries in children and adolescents – William M. Hohl, MD
Musculoskeletal infections in children – Deborah Lehman, MD
Volume 35, Issue 02
January 21, 2012
The defense attorney's perspective – Timothy A. Weaver, Esq
Liability risks of electronic health records – Michael S. Victoroff, MD
Volume 35, Issue 01
January 7, 2012
Screening patients with spinal pain – Timothy C. Shen, MD
Psychologic assessment of patients with low back pain – Robert Hines, MD
Spinal care and evidence–based medicine: a reappraisal – Paul C. McCormick, MD

Orthopedics (Online First): we do not have a subscription

Dermatan sulphate in methoxy polyethylene glycol-polylactide-co-glycolic acid scaffolds upregulates fibronectin gene expression but has no effect on in vivo osteochondral repair

Biomechanical reconstruction of the hip: comparison between modular short-stem hip arthroplasty and conventional total hip arthroplasty

Change in limb length after high tibial osteotomy using computer-assisted surgery: a comparative study of closed- and open-wedge osteotomies

Conventional or navigated total knee arthroplasty affects sagittal component alignment

The relationship of anterior and rotatory laxity between surgical navigation and clinical outcome after ACL reconstruction

Clamp fixation to prevent unfolding of a suture knot decreases tensile strength of polypropylene sutures

Radiographic and clinical results of posterior dynamic stabilization for the treatment of multisegment degenerative disc disease with a minimum follow-up of 3 years

Chondroprotection Following Acute Joint Injury: Prevention of Osteoarthritis