The Effect of Long-term Alendronate Treatment on Cortical Thickness of the Proximal Femur.

Long-term alendronate treatment did not appear to cause thickened femoral cortices within the detection limits of our method. This finding contrasts with the notion that long-term alendronate treatment leads to generalized cortical thickening. Unnanuntana A, Ashfaq K, Ton QV, Kleimeyer JP, Lane JM. Clin Orthop Relat Res. 2011 Jul 20. [Epub ahead of print] PMID: 21773861