“Would you like some Indian food with that operation”? Curcumin Protects Against Ischemia/Reperfusion Injury in Rat Skeletal Muscle.

Administration of curcumin significantly decreased tissue protein carbonyl levels as a marker of protein oxidation activities (PO) in skeletal muscle compared with the injured-untreated group. Curcumin reversed the increase of MDA levels to a considerable extent, thereby confirming its antioxidant role in IRI. Decreased SOD, CAT, and GSH activities by IRI are reversed by the administration of curcumin. Levels of circulating inflammatory cytokines TNF-a and IL-1b were reduced in curcumin-treated group in comparison to the IRI non-treated group. Bank J, Song DH. J Surg Res. 2011 Nov 19. [Epub ahead of print] No abstract available. PMID: 22261585 PDF