Researchers at Duke University Medical Center used new tools they developed to analyze knees and hips and discovered that osteoarthritic knee joints are in a constant state of repair, while hip joints are not.
"This suggests the knee has capacity for repair we didn't know about and the main treatment strategy probably would need to focus on turning off the breakdown of knee tissue," said Virginia Kraus, M.D., Ph.D., professor of Rheumatology and Immunology at Duke.
The findings, published in the Journal of Biological Chemistry on Friday, Feb. 10, suggest that for hips, however, turning off the degenerative process might not be enough. The hips would need a treatment to both turn off of the degenerative process as well as stimulate factors that could help to begin repair. Eurekalert!
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