Impact of restriction of cefepime use on the antimicrobial susceptibility of Gram-negative bacilli related to healthcare-associated infections in an orthopedic hospital.

Restriction of cefepime use had a positive impact on K. pneumoniae and Enterobacter spp, given that after this restriction, their susceptibilities to ciprofloxacin improved. However, for A. baumanii, the impact was negative, given the worsening of susceptibility to imipenem. Oliveira PR, Paula AP, Dal-Paz K, Felix CS, Rossi F, Silva JS, Lima AL. Infect Drug Resist. 2011;4:149-54. Epub 2011 Aug 4. PMID: 21904460 PDF