Inflammatory Response Is Associated with Critical Colonization in Combat Wounds.

Modern combat- or blast-related injuries are characterized by devastatingly massive zones of injury that violate soft tissue, bone, and neurovascular structures. In our translational research program, we have determined that healing of traumatic combat wounds is dependent on the immune response. Although the majority of combat wounds are not critically colonized with bacteria, there exists a correlation between critical colonization and the concentration of inflammatory cytokines and chemokines measured in wound effluent or patient serum. Brown TS, Hawksworth JS, Sheppard FR, Tadaki DK, Elster E. Surg Infect (Larchmt). 2011 Sep 21. [Epub ahead of print] PMID: 21936666

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Inflammatory biomarkers in combat wound healing JS Hawksworth, A Stojadinovic, FA Gage…  Annals of Surgery 2009 - journals.lww.com
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