Hyponatremia and bone: an emerging relationship.

Hyponatremia is the most common electrolyte disorder and is mainly known for its neurological complications. New studies suggest previously unrecognized complications of hyponatremia, including falls, osteoporosis and fractures. Because these novel associations are mainly derived from epidemiological studies, it remains unclear whether hyponatremia has a direct effect on bone or whether it is a surrogate marker of another etiology. Hoorn EJ, Liamis G, Zietse R, Zillikens MC. Nat Rev Endocrinol. 2011 Oct 25. [Epub ahead of print] PMID: 22024973